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ALS News
Contents
Volume 261 • January 25, 2006
ALSNews is a monthly electronic newsletter to keep users and other interested parties informed about developments at the Advanced Light Source, a national user facility located at Lawrence Berkeley National Laboratory, University of California. We welcome suggestions for topics and content.
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Depth profile of uncompensated spins
in an exchange-bias system

The phenomenon known as exchange bias at the interface between a ferromagnet and an antiferromagnet is currently a subject of intense research because of its applications in the magnetic recording and read-head industries. An international collaboration headed by researchers from the University of California, San Diego, has used resonant x-ray scattering and polarized-neutron reflectometry to determine the depth-dependent magnetization in an exchange-biased sample. These results provide atomic-level insights into the mechanism of exchange bias, specifically the involvement of mutual interactions between two kinds of uncompensated spins in the antiferromagnet and spins in the ferromagnet. Full story.

Spin Depth Profiles

Publication about this research: S. Roy, M.R. Fitzsimmons, S. Park, M. Dorn, O. Petracic, I.V. Roshchin, Z.-P. Li, X. Batlle, R. Morales, A. Mishra, X. Zhang, K. Chesnel, J.B. Kortright, S.K. Sinha, and I.K. Schuller, "Depth profile of uncompensated spins in an exchange bias system," Phys. Rev. Lett. 95, 047201 (2005).

Contact: Sujoy Roy, sujoy@physics.ucsd.edu

First detailed look
at RNA Dicer

Scientists have gotten their first detailed look at the molecular structure of an enzyme that Nature has been using for eons to help silence unwanted genetic messages. A team of researchers with Berkeley Lab and the University of California, Berkeley, used x-ray crystallography at ALS Beamlines 8.2.1 and 8.2.2 to determine the crystal structure of Dicer, an enzyme that plays a critical role in a process known as RNA interference. The Dicer enzyme is able to snip a double-stranded form of RNA into segments that can attach themselves to genes and block their activity. With this crystal structure, the researchers learned that Dicer serves as a molecular ruler, with a clamp at one end and a cleaver at the other end a set distance away, that produces RNA fragments of an ideal size for gene-silencing. Full story.

Dissecting the Dicer

Publication about this research: I.J. MacRae, K. Zhou, F. Li, A. Repic, A.N. Brooks, W.Z. Cande, P.D. Adams, and J.A. Doudna, "Structural basis for double-stranded RNA processing by Dicer," Science 311, 195 (2006).

Contact: Jennifer Doudna, doudna@berkeley.edu

Formation of ALS Staff Safety
Committee (ALSSC)

Safety First graphicIn the interest of promoting a safer working environment at the ALS and to maintain the confidence of the staff and users, the Acting ALS Division Director has established a multidisciplinary safety committee to review ALS environment, safety, and health (ES&H) procedures as concerns and incidents warrant.

Specifically, the charter of the committee is to

  • Review ALS safety protocols and recommend changes to procedures and, if necessary, organizational changes.
  • Be involved in investigating incidents, recommending corrective actions to ALS management, and monitoring follow-up.
  • Disseminate information to ALS staff in a timely manner on the current status of investigations, corrective actions, and follow-up of safety incidents.
  • Anticipate potential safety issues and recommend changes; bring any unaddressed safety concerns to the attention of ALS management.

The committee's first task is to recommend implementation plans for the corrective actions put forward by a subcommittee of the Berkeley Lab Radiation Safety Committee, formed in response to recent shielding control incidents. Specifically, the committee is to prioritize the recommendations and decide which can be addressed quickly to make the ALS safer.

The current avenues for raising safety concerns remain the same: discussions with your supervisor and in safety circles, contacting ALS ES&H personnel, contacting a beamline coordinator, and alerting the control room. In addition, if users or staff feel that their safety concerns are not adequately addressed through these avenues, they may approach the ALSSC. The members are listed below:

Ken Woolfe (chair)
Dan Colomb
Susanna Jacobson
Nicholas Kelez
Michael Martin
Howard Padmore
Corie Ralston
Art Robinson
Christoph Steier
Ben Feinberg (ex-officio)

Contact: Ken Woolfe, KDWoolfe@lbl.gov

UEC Corner: Notes from the Users'
Executive Committee

by Clemens Heske

Clemens HeskeThe ALS Users' Executive Committee (UEC) is a group of elected ALS users that represents the ALS user community, both towards ALS and Berkeley Lab management, as well as towards external persons and groups such as members of the Department of Energy (DOE), committees reviewing the ALS, and elected officials in Washington and elsewhere.

Please welcome the newly elected members of the UEC: Alessandra Lanzara, Elke Arenholz, and Hendrik Ohldag. The other returning members of the UEC are Tony van Buuren, Jinghua Guo, Amanda Hudson, Simon Morton, Corie Ralston, and Ed Westbrook. I want to thank Greg Denbeaux, who was chair of the UEC last year, for all of his efforts. I'm pleased to have the opportunity to represent you as chair of the UEC this year. Tony van Buuren is the vice-chair this year and will be the chair next year.

We are here to support your needs, so please contact me (heske@unlv.nevada.edu) or anyone else on the UEC with any questions, comments, complaints, or praise. You can find the contact information of all UEC members online. In view of the two different areas of UEC activity mentioned above, we would be very happy to learn about your thoughts on questions like parking, user housing, support on the experiment floor, staging areas, etc. If there are things to improve, we would want to know, and if things are going well, we would love to pass the information on to the external community.

This is going to be a busy year for the UEC. As Greg Denbeaux pointed out in the last ALSNews, budget issues in Washington are likely to become even more important in the near future. The Users' Associations at the light sources across the country have formed a group to work on outreach and education to help ensure that people understand the importance of these facilities, and Corie Ralston is representing the ALS UEC in this activity. Please contact her at cyralston@sff.net if you have any questions or suggestions. Other activities of the UEC will include the planning of the 2006 Users' Meeting, and we will soon post the dates so that you can mark your calendars.

Again, please don't hesitate to contact me with any questions or concerns—I look forward to a productive and interesting year for our Advanced Light Source!

Contact: Clemens Heske, heske@unlv.nevada.edu

Archaeology studies using
microdiffraction at Beamline 7.3.3

One scientific discipline that shows increasing interest in spatially resolved synchrotron diffraction techniques is archeology. The use of x-ray microdiffraction with either white or monochromatic beam provides structural information on minute amounts of materials contained in ancient artifacts, which in turn give some clues as to how these artifacts were made. Terra-cotta warriorAt Beamline 7.3.3, experiments have been carried out to identify mineral phases in Gallo-Roman terra sigillata ceramics from the first to third century AD. Phase distribution and grain sizes provide information about the firing process as well as on the origin of the raw materials. Another ongoing project is the determination of the long-lost recipe to fabricate the Chinese Purple pigment used to paint the terra-cotta army statues of the Qin Dynasty (200 BC). Such studies will benefit greatly from the construction of the new superbend Beamline 12.3.2 microdiffraction system. It is expected that operations will be able to move from Beamline 7.3.3 in the spring of 2006, after which there will be a period of extensive commissioning of the new system. The use of a superbend and new optics should allow an increase in flux and strain sensitivity by a factor of 10 and an improvement in spatial resolution to about 100 nm.

Contact: Nobumichi Tamura, NTamura@lbl.gov

Terahertz Science and
Technology Network

There has been a recent explosion of interest in using terahertz (THz) radiation to investigate questions in chemistry, biology, physics, medicine, and materials science. Simultaneously, there has been a rapid development of a broad array of experimental tools for working with THz radiation. In response, a collaboratory* called the THz Science and Technology Network has been proposed. The Network's goals are to lower barriers to experimental and theoretical research involving THz radiation, to foster interaction and technological innovation, and to expand the THz community.

The Network will provide necessary infrastructure that is beyond the means of any individual investigator. A key component of the Network is a set of nodes with research tools and expertise that together span the current state of the art. These nodes will provide open access to all qualified users. A second important component is an extensive Web site that provides thumbnail sketches of terahertz research areas, detailed descriptions of the nodes, expert contact lists, a virtual journal, a spectral database, calibration data, educational materials, an interactive virtual spectrometer, a buyer's guide, how-to manuals, press releases, a jobs clearinghouse, conferences, and frequently asked questions. Other components include education, outreach, development of health and calibration standards, interface with industry, and international cooperation.

THz Science & Technology Network logo

*A collaboratory is "an organizational entity that spans distance, supports rich and recurring human interaction oriented to a common research area, and provides access to data sources, artifacts and tools required to accomplish research tasks." From the National Academy of Sciences Science of Collaboratories 2003 report.

Contact: Michael C. Martin, MCMartin@lbl.gov

Last call for publications: Deadline
extended to Friday, January 27

The ALS is compiling a publications list for a Division Review coming up in March. The DOE will be looking at publications from the last three years, so please check our online database to make sure that all of your ALS-related publications from 2003–2005 are included. The deadline for submitting publications has been extended to Friday, January 27, 2006.

To check the database and/or submit publications, go to the ALS Reporting Publications Web page and follow the instructions there. When submitting a publication, if you don't have a certain piece of information (e.g., page number or month published), type "n/a" in the field. The User Services Office will attempt to track it down. Be sure you are using an up-to-date Web browser—Netscape 6 or 7 or Microsoft Internet Explorer 5.0 or greater. If you don't, you will lose data when you hit the "Back" key.

Checklist graphicDon't forget to include all Ph.D. and Masters theses, patents, and book chapters in your publication submissions. Theses are especially important as they are used to evaluate the educational component of the national facilities. We very much appreciate your efforts and apologize for the early deadline. It is imperative that we accurately report the number of ALS-related publications to the DOE and that we include them for this review. Publications are a primary metric used by DOE in the funding process. Remember, if it's on your CV, and all or part of the work was done at the ALS, it should be in our database!

Contact: Barbara Phillips, BEPhillips@lbl.gov

 

Depth profile of uncompensated spins in an exchange-bias system

First detailed look at RNA Dicer

Formation of ALS Staff
Safety Committee (ALSSC)

UEC Corner: Notes from the Users' Executive Committee

Archaeology studies using microdiffraction at Beamline 7.3.3

Terahertz Science and Technology Network

Last call for publications: Deadline extended to Friday, January 27

 
News Links

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Advanced Light Source to analyze 'Stardust'

Studies reveal how new drug may overcome deadly mutation that causes leukemia

 
Operations

RING STATUS

SCHEDULES

For the user runs from
December 19–January 23:

Beam reliability*: 97.7%

Completion**: 93.2%

There were no significant interruptions.

*Time delivered/time scheduled
**Percent of scheduled beam delivered without interruption

Requests for special operations use of the "scrubbing" shift should be sent to Jan Pusina (ALS-CR@lbl.gov, x4738) by 1:00 p.m. Friday.

The Accelerator Status Hotline at (510) 486-6766 (ext. 6766 from Lab phones) features a recorded message giving up-to-date information on the operational status of the accelerator.

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EDITORS
Lori Tamura
Art Robinson
Liz Moxon

DESIGNER
Greg Vierra

LBNL/PUB-948

This work was supported by the Director, Office of Science, Office of Basic Energy Sciences, of the U.S. Department of Energy under Contract No. DE-AC02-05CH11231. Disclaimer.