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ALSNews Vol. 362 Print
Tuesday, 24 March 2015 14:29

Protein Instability and Lou Gehrig's Disease

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A new study uses small-angle x-ray scattering as well as several advanced biophysical techniques to link protein instability to the progression of a lethal degenerative disease: amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease. Read more...

Contact: Elizabeth Getzoff and John Tainer

Molecular Structure of Water at Gold Electrodes Revealed

ALS researchers have now made a first-ever observation of the molecular structure of liquid water at a gold surface under different charging conditions. This marks the first time that the scientific community has been able to achieve such high sensitivity in an in-situ environment under working electrode conditions. Read more...

Contact: Miquel Salmeron

New Metrology Instrumentation Extends Moore's Law

As Moore's Law progresses and the semiconductor industry moves into the next phase of precision, new metrology instrumentation is required for success. The ALS, in collaboration with aBeam Technologies and Argonne National Laboratory, has met this need with the development of the finest metrology tool in the world, able to measure line widths down to 1.5 nanometers. "Qualifying and tuning metrology systems at the nanoscale is not easy," says ALS researcher Valeriy Yashchuk, "but we designed a test pattern that is capable of characterizing nano-metrology systems over their entire dynamic range." Read more...external link

ALS Science Briefs

Each month the communications team publishes two science highlights in ALSNews, yet there are many other interesting science stories that we would like to share with ALS staff and the user community. Since 2011, we have published more than 45 Science Briefs, short articles (~250 words) that provide a quick snapshot of recently published work. Here are the most recent contributions:

terra sigillata
Terra Sigillata: Evolution of Roman Ceramics Reflects Changes in Technology, Life


Decoding Ancient Ocean Acidification Signals from Plankton Shells

2015 General User Proposals: Timeline for March 4 Submissions

user office updates

The User Office received 279 new General User Proposals (GUPs) and 421 Beam Time Requests (BTRs) for the 2015-2  running cycle. The User Office has processed all the proposals. Users submitting new proposals should have received an email inviting them to log in to ALSHub to review the proposal PDF that will be sent to reviewers. Read more...


Contact: Susan Bailey


Operations Update

For the user runs from February 19 to March 15, 2015, the beam reliability [(time scheduled - time lost)/time scheduled)] was 98.5%. For this period, the mean time between failures (MTBF) was 53.3 hours, and the mean time to recovery (MTTR) was 58 minutes. There were no significant interruptions.

Detailed information on reliability is available on the ALS reliability bulletin board, which is located in the hallway between the ALS and the control room in Building 80. Questions about beam reliability should be directed to Dave Richardson ( This e-mail address is being protected from spambots. You need JavaScript enabled to view it , x4376).


Long-term and weekly operations schedules are available online. Requests for special operations use of the "scrubbing" shift should be sent to  ( This e-mail address is being protected from spambots. You need JavaScript enabled to view it ) by 1:00 p.m. Friday. The ring status can be seen in real time at

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